Philips Genomics Workspace enables integration of the largest-scale FDA-cleared cancer genetic test at NYU Langone Health

August 3, 2021

  • Philips and NYU Langone Health Department of Pathology, a premier NCI (National Cancer Institute) designated comprehensive cancer center, collaborate for genomic processing, interpretation and reporting
  • Leveraging Philips Genomics Workspace hosted on Philips HealthSuite, NGS (Next-Generation Sequencing) is integrated directly into NYU Langone’s EMR for seamless, secure data sharing and integrated decision-making

Amsterdam, the Netherlands – Royal Philips (NYSE: PHG, AEX: PHIA), a global leader in health technology, today announced that New York Langone Health’s Department of Pathology will leverage Philips Genomics Workspace (formerly part of IntelliSpace Precision Medicine Platform) to integrate into their EMR (electronic medical record) environment. This will enable the largest cancer sequencing test in the industry, helping to guide more confident treatment decisions and care pathways for patients who have received a cancer diagnosis.

Genetic test for all cancers designed by NYU Langone’s molecular pathologists
Cleared by the FDA (U.S. Food and Drug Administration) earlier this month under its 510(k) designation for clinical lab use, the NYU Langone Genome PACT (Profiling of Actionable Cancer Targets) test detects changes in the DNA code of 607 genes linked by past studies to the development of multiple types of cancer. The number of genes cancer types assayed is the largest among academic genomic sequencing tests of its kind.

PACT uses next-generation sequencing (NGS) technology, which can read the sequence of the molecular ‘letters’ making up DNA code within hundreds of genes simultaneously, and covers the most genes of any FDA-cleared NGS test to-date. The technology matches the genetics of each patient’s tumor cells with a growing number of approved therapies targeted to address specific sets of cancer-causing DNA changes.

“The work currently underway at NYU Langone is ground-breaking in the area of genomic sequencing and we are honored to be teaming on the development efforts, including building an interface between the new test and NYU Langone Health’s electronic medical records system,” said Louis Culot, General Manager of Oncology Informatics at Philips. “Philips Genomics Workspace, hosted on cloud-based Philips HealthSuite, will help facilitate the integration into the EMR so tests can be seamlessly ordered, reviewed, and shared by a patient’s care team.”

“PACT reaffirms the goal behind its design, which was to provide our patients with the best understanding of the genetic changes driving their cancers,” said PACT designer Matija Snuderl, MD, director of Molecular Pathology and Diagnostics in the Department of Pathology at NYU Langone Health. “Knowing the genetics of their tumor can help to determine which therapies will work for a given patient and their eligibility for specific clinical trials. Beyond the genetic changes that are important to the field now, we also wanted PACT to detect the changes anticipated to be important in diagnosis and treatment of cancer over the next five to ten years.”

Philips end-to-end oncology solutions driving a clear path to precision cancer care
According to the National Cancer Institute, patients today usually receive the same treatment as others who have same type and stage of cancer, despite growing evidence that they may respond differently [1]. Philips’ approach to precision medicine is to arm care teams with expert clinical guidance and a holistic view of the patient’s genotypic (the set of genes in the DNA) and phenotypic (observable characteristics influenced by environmental and lifestyle factors) information in order to make decisions efficiently, collaboratively and accurately. Recognizing the growing need for technological advancement in oncology care – from early detection to diagnosis to treatment to survivorship – Philips connects areas such as pathology, genomics, molecular/multi-disciplinary tumor boards, therapy decision making, molecular and imaging phenotyping, so clinicians can have easy access to the insights they need to provide high-quality personalized care.

With Philips Genomics Workspace, oncologists can map a patient’s unique characteristics to a therapy that is best suited for them and provide evidence on why that therapy is preferable. Philips genomics solution combines individual institution genomic knowledge bases and general industry knowledge bases, to help molecular pathologists interpret genomic data and to provide clinicians with ways to enable improved patient care. Visit Philips Precision Medicine to learn more.

[1] https://www.cancer.gov/about-cancer/treatment/types/biomarker-testing-cancer-treatment.

For further information, please contact:

Kathy O’Reilly
Philips Global Press Office
Tel.: + 1 978-221-8919
E-mail: kathy.oreilly@philips.com
Twitter: @kathyoreilly

Greg Williams
Research Communications Director
NYU Grossman School of Medicine
Tel: +1 212-404-3500
E-mail: Gregory.williams@nyulangone.org

About Royal Philips

Royal Philips (NYSE: PHG, AEX: PHIA) is a leading health technology company focused on improving people’s health and well-being, and enabling better outcomes across the health continuum – from healthy living and prevention, to diagnosis, treatment and home care. Philips leverages advanced technology and deep clinical and consumer insights to deliver integrated solutions. Headquartered in the Netherlands, the company is a leader in diagnostic imaging, image-guided therapy, patient monitoring and health informatics, as well as in consumer health and home care. Philips generated 2020 sales of EUR 17.3 billion and employs approximately 77,000 employees with sales and services in more than 100 countries. News about Philips can be found at www.philips.com/newscenter.

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COVID: Sarawak southern zone’s move to Phase Three of PPN postponed

KUCHING, Aug 3 — Sarawak’s southern zone, covering Kuching, Bau, Lundu, Samarahan, Simunjan, Asajaya, Serian and Tebedu will not be moving to Phase Three of the National Recovery Plan (PPN ) tomorrow as scheduled.

 

The State Disaster Management Committee (JPBN) is a statement announced that the move was postponed until the COVID-19 cases in this zone showed a declining trend.

 

“This means that only the northern zone (Miri, Limbang, Bintulu), central zone (Sibu, Mukah, Kapit) and western zone (Sarikei, Betong, Sri Aman) will move to Phase Three of PPN beginning tomorrow.

 

 

Yeserday, Prime Minister Tan Sri Muhyiddin Yassin reportedly announced that Perlis, Sarawak and the Federal Territory of Labuan would be moving to Phase Three of PPN.

 

The decision on Sarawak’s southern zone was also agreed upon by JPBN after receiving advice from medical experts and based on the existing standard operating procedure (SOP).

 

 

 

Source: BERNAMA News Agency

Walk-in vaccinations for seniors begin in Perak

IPOH, Aug 3 — Perak today started COVID-19 walk-in vaccinations for senior citizens at vaccination centres, said state Health director Datuk Dr Ding Lay Ming.

 

She said walk-in vaccinations were available for the afternoon session, from 2 pm to 5 pm.

 

“Yes, (walk-in vaccinations) only during the afternoon session and only for senior citizens aged 60 and above,” she said briefly when contacted by Bernama today.

 

 

Today, there was an internal memo from Dr Ding saying that the COVID-19 Immunisation Task Force  had ordered the implementation of COVID-19 vaccination on a walk-in basis throughout the state.

 

According to the Special Committee on Ensuring Vaccine Supply Access, 1,513,357 people have registered for inoculation in Perak, with 781,493 having received the first dose.

 

 

 

Source: BERNAMA News Agency

SSM temporarily shutting down MyLLP to upgrade

KUALA LUMPUR, Aug 3  – The Companies Commission of Malaysia (SSM) announced today that the MyLLP system developed in 2013 for transactions by limited liability partnership (LLP) entities is due for an upgrade, therefore it will be shut down from Aug 6 – 18, 2021.

 

“The new system can be accessed via www.ssm.com.my or www.ssm4u.com.my beginning Aug 19, 2021,” the statement said today.

 

It added that as at June 30, 2021, there were 28,577 LLPs registered under the LLP Act 2012 and that the system shutdown would also affect 42,994 compliance officers.

 

 

SSM encouraged system users to get their queries resolved as soon as possible to prevent complications or to wait till the new MyLLP is launched.

 

It said that under the new system, transactions like user registration, name reservation and change in particulars will be much easier.

 

Users will also be able to file annual declarations and apply for a name change, extension of time and more.

 

 

For more information, visit www.ssm.com.my, call (03) 7721 4000 or e-mail: enquiry@ssm.com.my.

 

 

 

 

Source: BERNAMA News Agency

Student riding pillion dies as vehicle crashes into motorcycle

 

SIBU, Aug 3 — A female student was killed while her friend suffered minor injuries after the motorcycle they were on was hit by another vehicle at Jalan Julau/Nanga Entabai in Sarikei here yesterday.

 

Julau district police chief DSP Andam @ Sulin Brayun said in the incident at about 9pm, Kemalia Fran George, 17, died while her friend, Feisyia Erwin Jeffery, 20, who was riding the motorcycle, sustained injuries.

 

“During the incident, the two friends were said to be heading towards a new residential area  to look for internet coverage when a vehicle rear-ended their machine,” he said in a statement.

 

 

He added that the victim was pronounced dead by a medical officer at the Julau health clinic, while the type and registration number of the vehicle that was involved in the incident has yet to be identified.

 

He said the body of the victim was sent to the Sarikei Hospital for further action and the case was being investigated under Section 41(1) of the Road Transport Act 1987.

 

 

 

Source: BERNAMA News Agency

 

COVID: Sabah records 1,010 positive cases, one new cluster – Masidi

KOTA KINABALU, Aug 3 — A total of 1,010 COVID-19 positive cases were recorded in Sabah today, with one new cluster detected, bringing the total number of infections in the state to 87,899, Sabah Local Government and Housing Minister Datuk Masidi Manjun said.

 

He said the new cluster, known as the Sangkabok cluster in Kuala Penyu, involved infections within the community, with the index case being a 62-year-old housewife who was confirmed positive after undergoing symptomatic screening at a private clinic on July 16.

 

“The index case had a history of travelling to Beaufort for medical treatment. Close contact and social contact tracing were conducted and 33 cases have been recorded so far,” he said in a statement tonight.

 

 

Masidi who is also the state government’s COVID-19 spokesman said 146 of the new cases recorded today were  from existing clusters, including the Pauh cluster (67 cases), the Tinabau cluster (13 cases) in Kinabatangan and Jalan Corak cluster in Tongod (21 cases).

 

Twelve deaths were also recorded today, namely four in Kota Kinabalu, Sandakan (three), Tawau (three) and one each in Tuaran and Putatan.

 

Overall, Masidi said the number of cases in Sabah today showed a drop of 156 cases, compared to the 1,166 cases recorded on Monday.

 

 

Kota Kinabalu still has the highest number of cases today, with 183 cases, followed by Sandakan (102 cases); Kinabatangan (92 cases); Tawau (90 cases); Tuaran (79 cases) and Penampang with 68 cases.

 

A total of 699 patients recovered, bringing the total recoveries in the state to 78,792 people, while 4,474 patients are still being treated, namely 947 in hospitals, public quarantine and low-risk treatment centres (3,471 people); jails and temporary detention centres (48 people) and eight in private facilities.

 

Meanwhile, Masidi said a total of 1.3 million vaccine doses had been administered under the Sabah-level National COVID-19 Immunisation programme as of today.

 

He said that the number of Sabahans who have registered as COVID-19 vaccine recipients via the various platforms provided also increased to 1.2 million or 43.8 per cent.

 

 

 

Source: BERNAMA News Agency

 

Second-dose vaccinations in Penang to increase next week

GEORGE TOWN, Aug 3 — The number of second-dose COVID-19 vaccinations in Penang is set to rise next week as the state aims to get 40 per cent of its population vaccinated, said Chief Minister Chow Kon Yeow.

 

“Beginning next week, more people will be receiving their second dose, and Penang will achieve a vaccinated population rate of 40 per cent and transition to Phase Three of the National Recovery Plan (PPN).

 

“Once again, I would like to stress that the state government is confident and committed to ensure that the entire state’s adult population will be vaccinated by early September,” he said in a statement today.

 

 

He said Penang was the sixth best state with a total of 1,100,073 doses administered so far, comprising 786,878 first jabs and 313,195 second jabs.

 

Chow added that in terms of population, Penang is also ranked sixth for first doses, with 44.4 per cent, above the national percentage of 44.3 per cent, and 17.7 per cent for second doses.

 

He also said the central COVID-19 Immunisation Task Force (CITF) has approved Penang’s application regarding the opening of a vaccination centre at Vangohh Eminent Hotel and Spa, which is expected to open on Aug 9 with a capacity of 2,000 daily doses, to ramp up vaccination in Central Seberang Perai district.

 

 

“With this new centre and the three existing ones in Central Seberang Perai district, we can administer 4,800 doses daily” he said.

 

 

 

 

Source: BERNAMA News Agency