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Virgin Hyperloop Unveils West Virginia, USA as the Location for Global Hyperloop Certification Center

The HCC will pave the way for the certification of hyperloop systems around the world – the first step towards commercial projects in places like India

Hyperloop Certification Center Rendering.

A rendering of the Hyperloop Certification Center in West Virginia. Design by Bjarke Ingels Group (BIG) and rendering by SeeThree.

NEW DELHI, India, Oct. 08, 2020 (GLOBE NEWSWIRE) — After years of testing and developing hyperloop technology at their full-scale test site, Virgin Hyperloop unveiled today that the global Hyperloop Certification Center (HCC) will be located in the US state of West Virginia.

“Today is one of the most exciting days in Virgin Hyperloop’s history,” said Sir Richard Branson, Founder of the Virgin Group. “We’re one step closer to making hyperloop travel a reality for people everywhere.”

The Hyperloop Certification Center (HCC) is a major milestone in the maturity and acceptance of hyperloop systems globally. A testament to Virgin Hyperloop’s technology advancement, it will enable global regulatory bodies to work with US federal authorities to establish and set global safety and industry standards for the new hyperloop category, which can subsequently be adopted and re-applied in other geographies.                               

“I’ve always been a big believer in the importance of competing against market transitions and Virgin Hyperloop is the clear leader in the future of transportation,” said John Chambers, former Executive Chairman and CEO of Cisco Systems, current founder and CEO of JC2 Ventures, and native of West Virginia. “With the development of the HCC in West Virginia, my home state, the company is one step closer to their dream of bringing their transformative technology to India and beyond. We look forward to supporting Virgin Hyperloop in this journey and imagining what is possible for the next generation of innovation, entrepreneurism, and inclusion, together.”

This announcement builds off of significant progress around the world on the regulatory front. In India, the Government of Maharashtra has deemed hyperloop a public infrastructure project and approved the Virgin Hyperloop-DP World Consortium as the Original Project Proponent (OPP) for the Mumbai-Pune hyperloop project. This is a landmark announcement for building the Pune-Mumbai hyperloop transportation system, recognizing hyperloop technology alongside other more traditional forms of mass transit. To forward this progress, the Principal Scientific Advisor (PSA) to the Government of India, Prof. Vijayraghavan, has set up an independent committee called the Consultative Group on Future of Transportation (CGFT) to explore the regulatory path for hyperloop.

This global regulatory momentum, combined with the advancements at the HCC, will pave the way for the certification of hyperloop systems around the world – the first step towards commercial projects, including those in India, while having the first human testing of the technology take place in the United States.

“The significance of this milestone cannot be overstated,” said Jay Walder, CEO of Virgin Hyperloop. “The establishment of the HCC enables regulatory authorities around the world to come together and establish global safety and industry standards for the new hyperloop category. This brings the hyperloop project connecting Mumbai to Pune in under 25 minutes – and others around the world – one step closer to reality.”

Beyond Maharashtra, there is enormous potential to connect the entire subcontinent. Last month, Virgin Hyperloop announced a ground-breaking partnership with Bangalore International Airports Limited (BIAL) to conduct a feasibility study for a proposed hyperloop corridor from BLR Airport. The study, which focuses on technical, economic and route feasibility, is expected to be completed in 2 phases of 6 months each. With speeds of up to 1,080 kmph, hyperloop could transport thousands of passengers per hour from BLR Airport to the city center in under 10 minutes, according to the preliminary analysis.

Virgin Hyperloop also signed a MoU with the State of Punjab’s Transport Department in December 2019 and hopes to expand on their relationship with Punjab as they continue exploring opportunities in northern India independent of their work in the western and southern regions of the country.

In Europe, the European Commission’s Directorate-General for Mobility and Transport (DGMOVE) has held numerous workshops over the past 2 years with hyperloop companies in conjunction with regulatory authorities and standards bodies – leading to the establishment of a baseline for the functional blocks of a hyperloop system and safety requirements. The European Commission is now carrying out a 9 month study to develop a safety regulatory approach for Europe, the results of which will be used by the Commission to develop the regulatory policy for hyperloop technologies. Active discussions are also underway with the three European regulatory authorities – the European Union Agency for Railways (ERA), the European Union Aviation Safety Agency (EASA), and the European Space Agency (ESA).

In the United States, the US Department of Transportation (USDOT) Secretary Elaine Chao and the Non-Traditional and Emerging Transportation Technology (NETT) Council unveiled a guidance document on a clear regulatory framework for hyperloop in the United States – providing a pathway to regulation and establishing a hyperloop project’s eligibility for federal funding.

Virgin Hyperloop aims to achieve safety certification by 2025, with commercial operations beginning in 2030.

About Virgin Hyperloop
Virgin Hyperloop is the only company in the world that has successfully tested hyperloop technology at scale, launching the first new mode of mass transportation in over 100 years. The company successfully operated a full-scale hyperloop vehicle using electric propulsion and electromagnetic levitation under near-vacuum conditions, realizing a fundamentally new form of transportation that is faster, safer, cheaper, and more sustainable than existing modes. The company is now working with governments, partners, and investors around the world to make hyperloop a reality in years, not decades. Learn more about Virgin Hyperloop’s technology, vision, and ongoing projects here.

Media Assets
Media assets can be found here. Please credit Virgin Hyperloop.

A photo accompanying this announcement is available at https://www.globenewswire.com/NewsRoom/AttachmentNg/a82adbb9-bce9-4f7c-bc59-639ab0188f4b

Media Contact         
Ryan Kelly
Vice President of Marketing and Communications
press@virginhyperloop.com
+1 (610) 442-1896

Wasabi Named a “Contender” in IDC MarketScape Public Cloud Storage Services 2020 Vendor Assessment

Wasabi recognized for straightforward pricing model and consistent growth

BOSTON, MA, Oct. 08, 2020 (GLOBE NEWSWIRE) — Wasabi, the hot cloud storage company, today announced it has been named a Contender in the IDC MarketScape Public Cloud Cold Storage Services 2020 Vendor Assessment (Doc # US46855520, September 2020). The report noted, “Wasabi is unique in the broader public cloud IaaS market because it offers a storage service that meets the definitions for both “hot” and “cold” in terms of access and cost requirements, all under a single price point — no other provider in this IDC MarketScape does this.”

In its assessment of public cloud storage service vendors, the IDC MarketScape recognized Wasabi for its infrastructure, customer reach, embedded technology, and growing partnerships. The IDC MarketScape also noted Wasabi’s flexibility to accommodate a range of storage workloads without compromising speed and the lack of ingress/egress fees or additional costs for data access as key value propositions.

According to the report, “Wasabi’s core strengths and differentiators in the cold storage market lie in the platform’s simplicity and speed. The vendor offers a single storage tier with a single price. This means that customers do not have to manage ingress/egress fees or additional costs for data access. This is an extremely attractive value proposition, specifically in the cold storage market where the cost of storage remains a major sticking point for customers. Wasabi builds onto this value proposition with features normally associated with ‘hot’ storage, like millisecond access time for objects and enterprise-class data availability and durability[…]this approach is what makes Wasabi such a unique and versatile provider in the cold storage market.”

“As companies collect and analyze more data, cloud cold storage platforms become increasingly important as a means to cost-effectively store, manage, and protect this data,” said Andrew Smith, research manager, Cloud Infrastructure Services at IDC. “Wasabi has proven its success in this market segment, demonstrating consistent growth of its direct customer base and channel partner ecosystem over the past three years. Wasabi’s focus on price simplicity and S3 API compatibility has become a recipe for success in the cloud cold storage market, particularly with storage software and services providers, who can quickly and cost-effectively integrate Wasabi as their cloud-based object storage back end.”

“It is incredibly gratifying for the IDC MarketScape to include Wasabi alongside some of the world’s largest, best-known technology brands,” said David Friend, Wasabi CEO, and co-founder. “Unlike those companies, however, Wasabi is focused on doing one thing really well: cloud storage. We’re proud of the recognition which is particularly critical as we build out both our technology infrastructure and our partner ecosystem and more.”

The IDC MarketScape’s recognition is the latest in a series of milestones for the company, following Wasabi’s recent $30 million funding round. Wasabi continues to expand its ecosystem, working with more than 3,100 total channel partners and over 200 technology partners to reach more than 18,000 customers. Last month, IT research firm Nucleus Research published a report touting Wasabi as a “progressive vendor” and a leading AWS alternative.

For more information about Wasabi, please visit https://wasabi.com/.

About IDC MarketScape

IDC MarketScape vendor assessment model is designed to provide an overview of the competitive fitness of ICT (information and communications technology) suppliers in a given market. The research methodology utilizes a rigorous scoring methodology based on both qualitative and quantitative criteria that results in a single graphical illustration of each vendor’s position within a given market. IDC MarketScape provides a clear framework in which the product and service offerings, capabilities and strategies, and current and future market success factors of IT and telecommunications vendors can be meaningfully compared. The framework also provides technology buyers with a 360-degree assessment of the strengths and weaknesses of current and prospective vendors.

About Wasabi

Wasabi provides simple, predictable, and affordable hot cloud storage for businesses all over the world. It enables organizations to store and instantly access an infinite amount of data at 1/5th the price of the competition with no complex tiers or unpredictable egress fees. Trusted by customers worldwide, Wasabi has been recognized as one of technology’s fastest-growing and most visionary companies. Created by Carbonite co-founders and cloud storage pioneers David Friend and Jeff Flowers, Wasabi has secured $110 million in funding to date and is a privately held company based in Boston.

Follow and connect with Wasabi on Twitter, Facebook, Instagram, and our blog.

InkHouse for Wasabi
Wasabi Technologies
wasabi@inkhouse.com

eVestment’s Next-Generation ESG Questionnaire Offers Deeper, More Useful Insights on this Fast-Growing Area

ATLANTA, Oct. 08, 2020 (GLOBE NEWSWIRE) — eVestment, a global leader in institutional investment data and analytics, has launched a new ESG questionnaire that builds on eVestment’s leadership in ESG data to expand and standardize ESG reporting. With input from institutional investors, consultants, managers and industry organizations, eVestment is bringing more insights and transparency to the ESG space. The new questionnaire is now available for all managers reporting data to eVestment and data and insights based on the new questionnaire are available to eVestment clients.

For investors and consultants, the new questionnaire offers more robust quantitative and qualitative data, allowing a deeper understanding of how ESG managers implement their approaches and what drives their decision making process.

For asset managers, the new questionnaire allows them to communicate their ESG strategies more completely and compellingly, giving managers who approach ESG thoughtfully and with rigor the ability to stand out from the competition.

“We heard from clients across the spectrum of eVestment users – investors, consultants and asset managers – that they need a more comprehensive way to review and present ESG data as this segment of the investment business continues to increase in importance around the world,” said Erika Spence, Head of Data Strategy at eVestment. “As the leader in institutional investment data and insights, this new questionnaire will bring unprecedented transparency and value to the reporting, sharing and reviewing of asset manager ESG data.”

The new questionnaire has 140 questions, compared to the previous questionnaire’s 40. In addition to more “yes/no” and other check-box style questions, the new questionnaire provides more options for narrative information and supplemental materials.

New questions include:

  • Does your firm engage or advocate for ESG improvements within its portfolio holdings?
  • Does your firm have policies that are intended to increase the level of gender and ethnic diversity of senior leadership and investment teams?
  • Do you have senior-level staff commitment and accountability mechanisms for the ESG investment implementation, as outlined in your policies, for this strategy?
  • Does the team provide attribution analysis measuring the impact analysis of their ESG decisions?
  • Under what circumstances would you purchase, hold or sell a security if relevant ESG issues were uncovered?

For existing strategies on the eVestment database that include ESG considerations, asset managers can update their current and past information in the new questionnaire to provide the historical perspective on their strategies that investors and consultants usually require when assessing managers and strategies. All new ESG strategies launched by asset managers will use the new questionnaire from inception.

This announcement aligns with eVestment parent company Nasdaq’s long-standing commitment to ESG-related advocacy and innovation to engage with stakeholders at all levels.

Investors, consultants and managers seeking more information on navigating the new questionnaire can contact solutions@evestment.com.

About eVestment

eVestment, a Nasdaq company, provides institutional investment data, analytics and market intelligence covering public and private markets. Asset managers and general partners reach the institutional marketplace through our platform, while institutional investors and consultants rely on eVestment for manager due diligence, selection and monitoring. eVestment brings transparency and efficiency to the global institutional market, equipping managers, investors and consultants to make data-driven decisions, deploy their resources more productively and ultimately realize better outcomes.

Press Contact
Mark Scott
mscott@evestment.com
678 238 0761

Cisco, Qwilt and Digital Alpha Define the Future of Content Delivery with New Open Caching Solution for Service Providers

News Summary

  • Companies introduce new model for streaming media delivery leveraging Open Caching architecture deployed at the edge of the service provider networks; it offers unprecedented levels of quality with open, global APIs endorsed by the Streaming Video Alliance
  • Innovative business model enables zero-capex and limited-risk deployment, helping service providers generate new revenue as active participants of the content delivery value chain
  • BT has adopted this solution to deliver high-quality streaming experiences across its network to its customers on behalf of global content providers

SAN JOSE, Calif. and REDWOOD CITY, Calif., Oct. 08, 2020 (GLOBE NEWSWIRE) — Cisco, Qwilt and Digital Alpha (DA) announced today how together they are disrupting the commercial Content Delivery Network (CDN) market with a new as-a-service offering based on Open Caching, with BT as the flagship customer.

Streaming content is increasingly delivered in 4K and soon 8K, supporting augmented and virtual reality (AR/VR) applications across multiple devices, over wireline and wireless connections. This drives network capacity demands, with consumer internet video traffic expected to comprise 82% of all (consumer) internet traffic by 2022, (up from 73% in 2017.)1

Resulting performance requirements are accelerating the shift away from traditional content delivery models, opening up the opportunity for service providers to use their edge assets to deploy their own distributed CDN capabilities and become more active participants in the streaming media delivery value chain.

Open Caching, an open architecture developed and endorsed by the Streaming Video Alliance, offers a platform that federates content delivery infrastructure deployed deep inside service provider networks, into a global CDN with open APIs for content publishers. It is designed to help service providers easily deploy an edge CDN footprint, offering them more control over content flows. It also caters to the needs of global and regional content providers for more capacity, consistency in content delivery and performance assurance.

Featuring Digital Alpha as the investing partner providing a unique funding solution, this partnership combines Qwilt’s innovative content delivery platform based on Open Caching, with Cisco’s edge compute and networking infrastructure to deliver the solution as-a-service to service providers of all sizes around the world.

BT, the UK’s leading telecommunications and network provider, in partnership with Qwilt, Cisco and DA has deployed this solution to add multiple terabits per second of capacity and provide cost-effective, high-quality streaming video to meet its growing demand in 2020 and beyond. Its decision to make the transition to Open Caching is based on the following requirements:

  • Deliver the highest-quality streaming experience across its entire network
  • Support an open architecture endorsed by the Streaming Video Alliance
  • Drive new revenue by becoming an active part of the content delivery value chain
  • Reduce content delivery costs by deploying CDN capabilities inside its network
  • Eliminate deployment costs using the innovative capex-free model

Industry and streaming ecosystem support for Open Caching is growing, with over 50 global service providers, technology vendors and content publishers actively involved in moving the content delivery industry in this direction.

“At BT we connect for good and streaming video has never been more important than in today’s challenging times,” said Neil McRae, Chief Architect, Managing Director for Architecture and Technology Strategy at BT. “Our mission at BT is to ensure our customers have the best experience every time and with record levels of streaming we needed to disrupt the status quo. Qwilt’s pioneering open caching platform together with Cisco’s cloud infrastructure gives BT the first 5G MEC capability in the UK to deliver premium quality video and on demand services.”

“Streaming video may be the killer app for the internet, but it doesn’t have to KILL the internet,” said Jonathan Davidson, Senior Vice President and General Manager, Mass Scale Infrastructure Group, Cisco. “With streaming video expected to represent north of 80% of traffic flowing through service provider networks in the coming years, content delivery is the first of potentially many services they can deploy from within to monetize their edge footprint in the 5G era. Marking this milestone together with Qwilt and Digital Alpha to enable edge cloud services for service providers, we can change the economics of the internet for the future, partnering with customers like BT to help them manage video traffic more effectively.”

“The way we consume video has changed, and content delivery must change with it,” said Alon Maor, CEO and Co-founder of Qwilt. “Our shared vision is to help service providers enable Open Caching in their networks and leverage edge computing as a fundamental component of their architecture. Together, we are helping many customers such as BT to accelerate their digital transformation in the UK and establish a content delivery platform that will serve as a foundation for today’s applications and new experiences coming in the future.”

“Digital Alpha is a trusted business partner, actively working with leading technology companies to support their market needs and growth opportunities with unique funding solutions,” said Rick Shrotri, Co-Founder, Managing Partner, Digital Alpha. “Our domain background and expertise lets us structure this innovative outcome-based model to support global service providers deploying their own CDNs with zero capex and limited risk. Working with our partners in conjunction with the leading content providers, we are committed to scaling this platform to service providers globally in the months ahead.”

Supporting resources:

About Cisco
Cisco (NASDAQ: CSCO) is the worldwide leader in technology that powers the Internet. Cisco inspires new possibilities by reimagining your applications, securing your data, transforming your infrastructure, and empowering your teams for a global and inclusive future. Discover more on The Network and follow us on Twitter at @Cisco.

Cisco and the Cisco logo are trademarks or registered trademarks of Cisco and/or its affiliates in the U.S. and other countries. A listing of Cisco’s trademarks can be found at www.cisco.com/go/trademarks. Third-party trademarks mentioned are the property of their respective owners. The use of the word partner does not imply a partnership relationship between Cisco and any other company.

About Qwilt
Qwilt’s unique Edge Cloud Platform and Open Caching software solutions help Internet Service Providers address the dramatic growth of streaming media on their networks and the need for a low latency, high scale infrastructure to support future applications. Qwilt’s cloud managed open platform, running on commodity compute and storage infrastructure and deployed close to consumers, creates a massively distributed Edge Cloud that supports applications such as Open Caching, 4K Live Streaming, AR, VR, Self-Driving Cars and IoT. This low latency Edge Cloud architecture enables a high-quality streaming experience for consumers on a massive scale. A growing number of the world’s leading cable, telco and mobile service providers rely on Qwilt for Edge Cloud applications.

Qwilt is a Founding Member of the Streaming Video Alliance and a leader of the Open Caching industry movement. Founded in 2010 by industry veterans from Cisco and Juniper, Qwilt is backed by Accel Partners, Bessemer Venture Partners, Cisco Ventures, Disrupt-ive, Innovation Endeavors, Marker and Redpoint Ventures. Learn more at www.qwilt.com.

About Digital Alpha
“Digital Alpha Advisors, LLC. (DA) is an investment firm focused on digital infrastructure and services required by the digital economy, with a strategic collaboration agreement with Cisco Systems, Inc. As part of this agreement, Digital Alpha has preferred access to Cisco’s pipeline of commercial opportunities requiring equity financing. Digital Alpha believes that it is the first fund focused on making private equity investments in the significant growth opportunities required to underpin the Digital Economy, including smart cities, next generation broadband networks, and enterprise data management and communication solutions. Digital Alpha was founded by Rick Shrotri, Head of the Global Infrastructure Funds (GIF) team at Cisco, and closed its first Fund – Digital Alpha Fund, LP – in 2017.”

About BT

BT Group is the UK’s leading telecommunications and network provider and a leading provider of global communications services and solutions, serving customers in 180 countries. Its principal activities in the UK include the provision of fixed voice, mobile, broadband and TV (including Sport) and a range of products and services over converged fixed and mobile networks to consumer, business and public sector customers. For its global customers, BT provides managed services, security and network and IT infrastructure services to support their operations all over the world. BT consists of four customer-facing units: Consumer, Enterprise, Global and its wholly-owned subsidiary, Openreach, which provides access network services to over 650 communications provider customers who sell phone, broadband and Ethernet services to homes and businesses across the UK.

For the year ended 31 March 2020, BT Group’s reported revenue was £22,905m with reported profit before taxation of £2,353m.

British Telecommunications plc is a wholly-owned subsidiary of BT Group plc and encompasses virtually all businesses and assets of the BT Group. BT Group plc is listed on the London Stock Exchange.

For more information, visit www.bt.com/about

Open Caching Architecture from the Streaming Video Alliance
Cisco and Qwilt’s content delivery solution is based on Open Caching specifications developed and approved by 60+ members of the Streaming Video Alliance (SVA) over the last five years. The Open Caching Working Group’s primary goal was to bring the streaming ecosystem together to create a new model for content delivery within internet service provider (ISP) networks. This industry initiative was driven by beliefs that building and operating content delivery technology closer to consumers will improve streaming quality and increase network capacity.

Press Contacts

Sara Cicero
Cisco Public Relations
stutzes@cisco.com

Qwilt Media Relations
media@qwilt.com
+1 650 249 6521


1 Source Cisco VNI Forecast 2017-2022

A video accompanying this announcement is available at https://www.globenewswire.com/NewsRoom/AttachmentNg/0a0f0b23-6098-4c51-b67f-daf2c1fde4b3

Combination Study with JS016 and LY-CoV555 for Patients with Mild-to-Moderate COVID-19 Symptoms Met Primary and Secondary Endpoints

— Viral load, symptoms, and hospitalizations or ER visits reduced
Request for EUA and BLA filings for the combination therapy anticipated in Nov 2020 and as early as 2Q2021, respectively
Large scale open-label study planned in coming weeks

SHANGHAI, China, Oct. 08, 2020 (GLOBE NEWSWIRE) — Junshi Biosciences (HKEX: 1877; SSE: 688180), a leading innovation-driven biopharmaceutical company dedicated to the discovery, development and commercialization of novel therapies, announced today that its global partner Eli Lilly and Company announced positive interim data on combination therapy with neutralizing antibodies JS016 (LY-CoV016) and LY-CoV555 in recently diagnosed patients with mild-to-moderate COVID-19 illness. Lilly intends to submit a request for Emergency Use Authorization (EUA) for the combination therapy in patients with mild-to-moderate COVID-19 in November 2020.

Data from a new interim analysis of Lilly sponsored BLAZE-1 clinical trial showed that combination therapy with two SARS-CoV-2 neutralizing antibodies reduced viral load, symptoms and COVID-related hospitalization and ER visits. The randomized, double-blind, placebo-controlled Phase 2 study evaluated JS016 (LY-CoV016) and LY-CoV555 (from Lilly’s collaboration with AbCellera), which bind complementary regions of the SARS-CoV-2 spike protein, for the treatment of symptomatic COVID-19 in the outpatient setting. The combination cohort enrolled recently diagnosed patients with mild-to-moderate COVID-19, who were assigned to 2800 mg of each antibody (n=112) or placebo (n=156).

The combination therapy significantly reduced viral load at day 11 (p=0.011), meeting the primary endpoint of the study. Most patients, including those receiving placebo, demonstrated near complete viral clearance by day 11. Further, combination treatment reduced viral levels at day 3 (p=0.016) and day 7 (p<0.001)—earlier time points during the course of infection when higher viral loads are typically seen. Combination therapy also significantly reduced time-weighted average change from baseline from day 1 to 11. An exploratory analysis showed that the proportion of patients with persistently high viral load at day 7 for combination therapy was lower (3.0 percent) versus placebo (20.8 percent), corresponding to a nominal p value of p<0.0001 without multiplicity adjustment. No emergent putative resistance variants have been observed thus far in patients treated with combination therapy.

Combination therapy also met prespecified clinical endpoints, including the time-weighted average change from baseline in total symptom score from day 1 to 11 (p=0.009). The improvement in symptoms was observed as early as 3 days after dosing. The rate of COVID-related hospitalization and ER visits was lower for patients treated with combination therapy (0.9 percent) versus placebo (5.8 percent), a relative risk reduction of 84.5 percent (p=0.049).

Combination therapy has been generally well tolerated with no drug-related serious adverse events. In LY-CoV555 monotherapy studies there have been isolated drug-related infusion reactions or hypersensitivity that were generally mild (two reported as serious infusion reactions, all patients recovered). Treatment emergent adverse events were comparable to placebo for both LY-CoV555 monotherapy and combination therapy.

Lilly is working to publish the data from the study in peer-reviewed journals as soon as possible.

Regulatory Update
Based on the combination therapy data, along with the previously disclosed findings for LY-CoV555 monotherapy, Lilly has engaged global regulators, including the FDA regarding potential EUA. Lilly expects to submit a request for EUA for combination therapy in November, pending clinical trial enrollment, once additional safety data accumulate and sufficient supply is manufactured. Lilly anticipates having data to support a biologics license application (BLA) submission for combination therapy as early as Q2 2021. Conversations with global regulators are ongoing.

The BLAZE-1 clinical trial (NCT04427501) continues to enroll a confirmatory cohort of higher-risk patients who have been recently diagnosed with mild-to-moderate COVID-19, testing the ability of the antibody combination to reduce the number of patients with persistently high viral load and reduce COVID-related hospitalizations. In addition, Lilly is studying lower doses of combination therapy and alternative delivery options in planned or ongoing clinical trials.

Open-Label Pragmatic Study in COVID-19 Outpatients
To generate additional efficacy and safety data, Lilly plans to initiate a pragmatic, open-label study in the coming weeks, enrolling patients treated with either monotherapy or combination therapy, with a focus on collecting data regarding hospitalizations, deaths and safety.

Moving forward, JS016 (LY-CoV16) and LY-CoV555 will be referred to as etesevimab and bamlanivimab, respectively.

About BLAZE-1
BLAZE-1 (NCT04427501) is a randomized, double-blind, placebo-controlled Phase 2 study designed to assess the efficacy and safety of JS016 and LY-CoV555 for the treatment of symptomatic COVID-19 in the outpatient setting. To be eligible, patients were required to have mild or moderate symptoms of COVID-19 as well as a positive SARS-CoV-2 test based on a sample collected no more than 3 days prior to drug infusion.

The combination arms of the trial enrolled mild-to-moderate, recently diagnosed COVID-19 patients, studying JS016 2800 mg plus LY-CoV555 2800 mg versus placebo.

The primary outcome measure for these completed arms of the BLAZE-1 trial was change from baseline to day 11 in SARS-CoV-2 viral load. Additional endpoints include the percentage of participants who experience COVID-related hospitalization, ER visit or death from baseline through day 29, as well as safety.

About etesevimab (JS016)
JS016 (also known as LY-CoV016) is a recombinant fully human monoclonal neutralizing antibody, which specifically binds to the SARS-CoV-2 surface spike protein receptor binding domain with high affinity and can effectively block the binding of the virus to the ACE2 host cell surface receptor. Point mutations were introduced into the native human IgG1 antibody to mitigate effector function. A SARS-CoV-2 challenge study was conducted in the rhesus macaques and showed LY-CoV016 is effective for both prophylactic and therapeutic venues against SARS-CoV-2 infection. Lilly licensed JS016 from Junshi Biosciences after it was jointly developed by Junshi Biosciences and Institute of Microbiology, Chinese Academy of Science (IMCAS). Junshi Biosciences leads development in Greater China, while Lilly leads development in the rest of the world.

Lilly has successfully completed a Phase 1 study (NCT04441931) of JS016 in healthy U.S. volunteers to evaluate the safety, tolerability, pharmacokinetics and immunogenicity. Junshi Biosciences has completed a similar Phase 1 study in healthy volunteers in China and has initiated Phase Ib/II trials in COVID-19 patients globally. Junshi Biosciences also intends to investigate the prophylactic potential of JS016 in high-risk population soon. JS016 has been well tolerated and no drug-related severe adverse events (SAEs) have been observed to date.

About bamlanivimab (LY-CoV555)
LY-CoV555 is a potent, neutralizing IgG1 monoclonal antibody (mAb) directed against the spike protein of SARS-CoV-2. It is designed to block viral attachment and entry into human cells, thus neutralizing the virus, potentially preventing and treating COVID-19. LY-CoV555 emerged from the collaboration between Lilly and AbCellera to create antibody therapies for the prevention and treatment of COVID-19. Lilly scientists rapidly developed the antibody in less than three months after it was discovered by AbCellera and the scientists at the National Institute of Allergy and Infectious Diseases (NIAID) Vaccine Research Center. It was identified from a blood sample taken from one of the first U.S. patients who recovered from COVID-19.

Lilly has completed enrollment and primary safety assessments of LY-CoV555 in a Phase 1 study of hospitalized patients with COVID-19 (NCT04411628) and long-term follow-up is ongoing. A Phase 2 study in people recently diagnosed with COVID-19 in the ambulatory setting (BLAZE-1, NCT04427501) is ongoing. Lilly recently initiated a Phase 3 study for the prevention of COVID-19 in residents and staff at long-term care facilities (BLAZE-2, NCT04497987). In addition, LY-CoV555 is being tested in the National Institutes of Health-led ACTIV-2 and ACTIV-3 studies of ambulatory and hospitalized COVID-19 patients.

About Junshi Biosciences
Founded in December 2012, Junshi Biosciences (HK: 1877; SH: 688180) is an innovation-driven biopharmaceutical company dedicated to the discovery, development and commercialization of innovative therapeutics. The company has established a diversified R & D pipeline comprising 26 innovative drug candidates and 2 biosimilars, with five therapeutic focus areas covering cancer, autoimmune, metabolic, neurologic, and infectious diseases. Junshi Biosciences was the first Chinese pharmaceutical company that obtained marketing approval for PD-1 monoclonal antibody in China and clinical trial application approval for anti PCSK9 monoclonal antibody from NMPA. The world’s first in human anti-BTLA antibody for solid tumors was officially approved for clinical trials by the FDA and NMPA. From this year onwards, Junshi Biosciences pooled its efforts with Chinese science institutions to co-develop JS016, China’s first neutralizing human monoclonal antibodies against SARS-CoV-2, that has entered clinical trial, part of our continuous innovation for disease control and prevention in China and beyond. We have about 2,000 employees in San Francisco and across Maryland in the United States, as well as Shanghai, Suzhou, Beijing, and Guangzhou, China. For more information, please visit: http://junshipharma.com.

About Eli Lilly and Company
Lilly is a global healthcare leader that unites caring with discovery to create medicines that make life better for people around the world. We were founded more than a century ago by a man committed to creating high-quality medicines that meet real needs, and today we remain true to that mission in all our work. Across the globe, Lilly employees work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to communities through philanthropy and volunteerism. To learn more about Lilly, please visit us at www.lilly.com and www.lilly.com/news.

Contact Information
IR Team:
Junshi Biosciences
info@junshipharma.com
+ 86 021-2250 0300

Solebury Trout
Bob Ai
bai@soleburytrout.com
+ 1 646.378-2926

PR Team:
Junshi Biosciences
Zhi Li
zhi_li@junshipharma.com
+ 86 021-6105 8800

Seaborn Appoints Steve Orlando as Chief Executive Officer

New Strategic Leadership Builds on Company’s History of Innovation and Leading Communications Services

BOSTON, Oct. 07, 2020 (GLOBE NEWSWIRE) — Seaborn Networks (“Seaborn”), a leading developer-owner-operator of submarine fiber optic cable systems, announces the appointment of Steve Orlando as its new Chief Executive Officer, effective October 1. With this strategic addition to the company’s executive leadership, Seaborn underscores its commitment to innovation, expertise, world-class services and comprehensive customer support.

A telecommunications industry veteran, Orlando brings 27 years of experience across senior leadership positions at Zayo Group, CenturyLink, Level 3, Global Crossing and Verizon Business. Orlando joins Seaborn from Zayo Group, where he served as the Senior Vice President of Fiber and Network Solutions. In this role, he led product, operations and network development to support indirect and direct sales for the organization across 18 states in the Central Region. As a proven leader with extensive cross-functional experience, Orlando will ensure Seaborn continues on its path of long-term growth in service of global connectivity.

“I’m thrilled to join the team at Seaborn as they deliver their signature technology-driven, client-first approach and best-in-class solutions,” comments Orlando. “I look forward to working alongside these industry leaders and collectively developing our world-class skills and transformational services.”

Seaborn’s connectivity solutions offer the stability of diversified subsea and terrestrial routes, delivering fault-resilient network architectures, enhanced security and improved quality of service. This industry-leading commitment to service is underpinned by the company’s operation of the Seabras-1 subsea cable system, connecting Brazil to the U.S. with the lowest latency and highest reliability across multiple POPs (Points of Presence) in São Paulo, Rio de Janeiro and the New York City metropolitan area. Seaborn’s industry leading service delivery and performance combined with IP and Ethernet service offerings provide a solution driven approach and commitment to always exceeding the service expectations of their customers.

“Seaborn is helping to transform global communications, and this appointment is sure to create a new era of success for the company and its customers,” comments Pete Hayes, Chairman of the Board at Seabras Group. “Steve brings a strong history of leadership and telecommunications experience, and he’s thoroughly equipped to lead Seaborn as it looks to address evolving global communications requirements.”

“Meeting the connectivity needs of customers is more important today than it has ever been, and as such, these strategic decisions are key for Seaborn’s role as a vital enabler,” comments Todd Bright, Partner and Head of Private Infrastructure Americas at global private markets investment manager Partners Group, which owns Seaborn on behalf of its clients. “I welcome Steve to the Seaborn team and look forward to the strategic insight, leadership and results he brings, not only to the company, but also its customers and the communications industry at large.”

About Seaborn
Seaborn addresses global communications needs across the Americas delivering wavelength, Ethernet private line and IP services. Unique among independent cable operators, Seaborn fully operates and maintains its submarine and terrestrial cable infrastructure. POPs, terrestrial backhaul, landing stations and subsea cable are all under Seaborn’s control. The Seaborn management team has designed, built, and operated more subsea cable systems than any other telecom management team including over 75 landing stations, 250 global POPs, and 250,000 km of subsea fiber optic cable. Visit www.seabornnetworks.com for more information or follow us on LinkedIn.

Media Contact:
Naaz Bax, Head of Marketing
media-relations@seabornnetworks.com

OKEx เพิ่มแดชบอร์ด Ether แบบเรียลไทม์ไปยังแพลตฟอร์มข้อมูลอนุพันธ์คริปโตของ skew

วัลเลตตา, มอลตา, Oct. 07, 2020 (GLOBE NEWSWIRE) — OKEx จุดแลกเปลี่ยนสกุลเงินคริปโตเคอเรนซี่และอนุพันธ์ชั้นนำระดับโลก กำลังเสริมความร่วมมือกับ skew โดยการเพิ่มแดชบอร์ดที่สองในแพลตฟอร์มที่ผู้ใช้สามารถดูข้อมูลการซื้อขาย Ether ได้จาก OKEx โดยรวมถึง ปริมาณการซื้อขาย ETH ล่วงหน้า, การซื้อขายแบบ Perpetual Swap และ Options OKEx เป็นบริการแลกเปลี่ยนแรกที่เปิดตัวแดชบอร์ดเชิงวิเคราะห์แบบเรียลไทม์สำหรับอนุพันธ์ Bitcoin และ Ether ใน skew โดยเน้นความมุ่งมั่นในการแลกเปลี่ยนที่โปร่งใส

เนื่องจากตลาดอนุพันธ์คริปโตได้รับความนิยมเพิ่มมากขึ้น จึงจำเป็นต้องมีข้อมูลที่น่าเชื่อถือสำหรับผู้ซื้อขายด้วยเช่นกัน Skew ได้สร้างชื่อเสียงในฐานะหน่วยงานที่เชื่อถือได้ในตลาดเฉพาะกลุ่มจากการมอบข้อมูลคริปโตชั้นนำโดยเน้นที่การซื้อขายอนุพันธ์ และได้รับการอ้างอิงโดยสื่อการเงินระดับโลก เช่น Bloomberg

ในเดือนพฤษภาคม OKEx ได้ก้าวสู่การเป็นแหล่งแลกเปลี่ยน Bitcoin แห่งแรกที่มอบความโปร่งใสในข้อมูลการซื้อขายอนุพันธ์ Bitcoin ของตนโดยประกาศเปิดตัวแดชบอร์ด BTC แบบเรียลไทม์ของตนกับ skew ความร่วมมือกับ skew ตั้งแต่นั้นมาได้เสริมความแข็งแกร่งด้วยแผนผังขั้นสูงสำหรับผู้ซื้อขาย เช่น สัญญาคงค้างในตลาดรวมของสัญญาซื้อขาย BTC ล่วงหน้า, และราคา BTC แบบ Perpetual Swap เปรียบเทียบกับจุดแลกเปลี่ยน ขณะนี้ OKEx กำลังมอบการวิเคราะห์และความโปรงใส่เชิงลึกในระดับเดียวกันในตลาดอนุพันธ์ Ether ของตน

“เรายินดีที่จะยกระดับความร่วมมือของเรากับ skew ซึ่งเป็นแหล่งข้อมูลการแลกเปลี่ยนอนุพันธ์ที่น่าเชื่อถือที่สุด และเราจะแบ่งปันคุณค่าในระดับเดียวกันในด้านการสนับสนุนความโปร่งใสในอุตสาหกรรมสืบต่อไป” Lennix Lai, หัวหน้าฝ่ายการตลาดเชิงพาณิชย์แห่ง OKEx แสดงความคิดเห็น

“พร้อมด้วยแดชบอร์ด Bitcoin และการหลอมรวมแผนผังเชิงวิเคราะห์ที่ซับซ้อนยิ่งขึ้นของเรา เราจะมีส่วนช่วยเหลือผู้ซื้อขายที่มีความเชี่ยวชาญให้มีความเข้าใจถึงวิธีแปลความข้อมูลเกี่ยวกับตลาด Ether โดยการเผยแพร่คำแนะนำเชิงลึกที่จะทำให้แผนผังมีประโยชน์มากกว่าทำให้กลัว และช่วยให้ผู้ซื้อขาย ณ เวลาตัดสินใจซื้อขาย”

นอกจากคำแนะนำสำหรับผู้ซื้อขายอนุพันธ์ Ether แล้ว Lennix Lai และ Quentin Issele ผู้เป็นรองประธานด้านการตลาดเชิงพาณิชย์แห่ง OKEx จะจัดงานพูดคุยอย่างเป็นกันเองไปพร้อมกับ Emmanuel Goh ผู้เป็นผู้ร่วมก่อตั้งและ CEO แห่ง skew ในวันที่ 8 ตุลาคม

เกี่ยวกับ OKEx

OKEx คือจุดแลกเปลี่ยนสกุลเงินคริปโตเคอเรนซี่และอนุพันธ์ชั้นนำระดับโลก โดยเสนอตลาดที่หลากหลายที่สุดซึ่งเป็นที่ที่ผู้ซื้อขาย นักขุด และนักลงทุนในองค์กรสามารถจัดการสินทรัพย์คริปโต เพิ่มโอกาสในการลงทุน และป้องกันความเสี่ยง เรามอบจุดแลกเปลี่ยนและการซื้อขายอนุพันธ์ รวมถึงสัญญาซื้อขายล่วงหน้า การซื้อขายแบบ Perpetual Swap และ Options จากคริปโตเคอเรนซี่หลักๆ พร้อมมอบความยืดหยุ่นให้กับนักลงทุนในการกำหนดกลยุทธ์เพื่อเพิ่มรายได้สูงสุดและลดความเสี่ยง

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