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Taconic Biosciences Expands Production of Critical Immunodeficient Model

Local Production of the CIEA NOG mouse® Model Now Available on the West Coast

RENSSELAER, N.Y., June 10, 2020 (GLOBE NEWSWIRE) — Taconic Biosciences, a global leader in providing drug discovery animal model solutions, announces local West Coast United States production of the immunodeficient CIEA NOG mouse® model.

Immunodeficient animal models are critical to the drug discovery ecosystem.  One of the most common contributors to the high product attrition rate for this industry is difficulty recapitulating the human biosystem in an animal model.  Immunodeficient models bridge this gap by enabling foreign tissue to interact with the animal, without rejection by that animals’ immune system.  Better replication of the human body in mice is a driving force in many revolutionary medical advances, including immuno-oncology and personalized medicine.

The CIEA NOG mouse® lacks the T, B, and natural killer (NK) cells that drive immune response. It is one of the most widely used severely immunocompromised mouse models.  The NOG mouse provides the foundation for Taconic’s extensive specialized models portfolio, which includes a variety of models with specific genetic and tissue modifications for greater precision.

West Coast production addresses the thriving California biomedical community with additional flexibility in planning experiments through multiple weekly deliveries, flexible ordering timelines, and reduced transit times for the animals.  NOG mice from this site are also available at Taconic’s EF health standard, a more restrictive health standard, valuable for immunodeficient models.

“Expanding the production of such a critical resource underscores Taconic’s commitment to providing researchers with easy access to the best animal model solutions,” commented Dr. Michael Seiler, vice president of commercial products at Taconic.  “The CIEA NOG mouse® is one of the most important animal models in the world because it is the foundation of a portfolio aimed at better replicating the human biosystem in an animal model.”

To learn more about the CIEA NOG mouse® or the NOG portfolio, please contact Taconic at 1-888-TACONIC (888-822-6642) in the US, +45 70 23 04 05 in Europe, or email info@taconic.com.

About Taconic Biosciences, Inc.

Taconic Biosciences is a fully-licensed, global leader in genetically engineered rodent models and services. Founded in 1952, Taconic provides the best animal solutions so that customers can acquire, custom-generate, breed, precondition, test, and distribute valuable research models worldwide. Specialists in genetically engineered mouse and rat models, microbiome, immuno-oncology mouse models, and integrated model design and breeding services, Taconic operates three service laboratories and six breeding facilities in the U.S. and Europe, maintains distributor relationships in Asia and has global shipping capabilities to provide animal models almost anywhere in the world.

Media Contact:

Kelly Owen Grover

Director of Marketing Communications

(518) 697-3824

kelly.grover@taconic.com

Pahang police cripple human trafficking syndicate, 11 agents nabbed

KUANTAN   Pahang police have crippled a human trafficking syndicate with the arrest of 11 men including a Myanmar national, who were believed to be syndicate agents in a raid in three districts in the state.

 

Pahang police chief Datuk Abd Jalil Hassan said the suspects, comprising 10 local men and one foreigner, aged between 28 and 70, were detained last Thursday after a-month surveillance under Op Benteng in Cameron Highlands, Lipis, and Temerloh.

 

“Preliminary investigation found the suspects are involved in bringing in victims from Indonesia, Nepal, Bangladesh and Myanmar to work as farm workers as there is a high demand for these workers.

 

 

 

 

“Each agent gets around RM1,000 to RM3,000 per head to smuggle the illegal immigrants into Malaysia, and there is a high demand in Cameron Highlands,” he said in a press conference at Pahang contingent police headquarters here today.

 

Abd Jalil said all the suspects would be detained until July 3 under the Security Offences (Special Measures) Act 2012 and the case is being investigated under Section 26J of the Anti-Trafficking in Persons and Anti-Smuggling of Migrants Act 2007.

 

In a separate development, Abd Jalil said police detained a couple aged 33 and 39 at an apartment in Cameron Highlands on Thursday for possessing about 4.4 kilogrammes of heroin worth RM40, 645 for the market here.

 

 

“The male suspect, who was working as a taxi driver, had allegedly used his vehicle to distribute the drugs around Cameron Highlands, Raub, and Lipis in the past six months. Urine tests found them to be positive for drugs.

 

He added the couple, who had previous drug-related criminal records, was remanded until tomorrow to facilitate investigations

 

The case is being investigated under Section 39B of the Dangerous Drugs Act 1952

 

 

 

Source: BERNAMA News Agency

Zoo Melaka reopens with min RM5 ticket price, max 500 people per session

Zoos have been allowed to reopen during the recovery movement control order (RMCO) which started today with Zoo Melaka implementing a 500 visitor limit per session, with two sessions held daily from 8.30am – noon and 2pm – 5pm.

 

Zoo Melaka and Melaka Bird Park director, Zanariah Khamis, said: “Zoo Melaka is spread over about 50 acres (20ha), so each session is limited to 500 people with a two-hour rest period from noon – 2pm to allow for cleaning and disinfection procedures.

 

“When purchasing tickets, only the head of the family is allowed to queue, but the name and contact details of every family member must be logged at the counter. Standard operating procedures (SOPs) must also be followed.”

 

 

 

She said that throughout the RMCO, and in order to encourage people to visit Zoo Melaka, there will be a ‘durian runtuh’ deal on tickets with the price for adult admission at RM10, and for children, senior citizens and people with disabilities (OKU) at RM5.

 

Zanariah said to bring back the glory days to Malaysia’s second largest zoo, “all kinds of things have been planned including introducing a petting zone, photo sessions with the animals, free feed the animals sessions, weekend meet the mascot sessions and so much more”.

 

She said the Zoo Melaka Donation Fund which was started in April has so far collected RM94,000 and food donations worth RM250,000.

 

 

She said donations to the zoo can be deposited in the Zoo Melaka CIMB bank account 8009600869, under the name ‘Zoo MPHTJ’.

 

“Companies, government bodies and individuals are also welcome to help ensure the continuity of food supplies, veterinary care and management by adopting the animals,” Zanariah said

 

Zoo Melaka was started in 1963 as a conservation, research and education centre, and is home to about 650 animals representing 150 species from around the world.

 

Yesterday, Senior Minister (Security Cluster), Datuk Seri Ismail Sabri Yaakob, said the Special Ministerial Committee on the Movement Control Order (MCO) Implementation gave the nod for zoos to reopen its doors today.

 

 

 

Source: BERNAMA News Agency

COVID-19: Positive cases surpass 34,000 in Indonesia, death toll at 1,959

JAKARTA  The number of positive COVID-19 cases in Indonesia has surged past 34,000, with a total of 1,959 deaths.

 

According to the Indonesian government’s spokesman on COVID-19, Achmad Yurianto, in the 24-hour period until noon today, 1,241 new positive cases and 36 deaths were reported.

 

“There are currently 34,316 positive cases while 14,242 patients are still under surveillance for COVID-19,” he said in his daily news conference broadcast on the official YouTube channel of the Indonesian Disaster Management Agency (BNPB).

 

 

 

The province of Jakarta still had the highest number of deaths namely 535 cases, followed by East Java (530 cases), West Java (161) and the rest in the other provinces of Indonesia.

 

 

 

Source: BERNAMA News Agency

 

COVID-19: Screenings to go on despite single digit cases – Health DG

The Ministry of Health (MOH) will continue to conduct COVID-19 screenings, despite having achieved single digit positive cases, for three consecutive days.

 

Health director-general Datuk Dr Noor Hisham Abdullah said screenings were ongoing as usual, including for the identified target groups.

 

Meanwhile, Dr Noor Hisham said the public must adhere to the standard operating procedure (SOP) outlined by the government during the Recovery Movement Control Order (RMCO).

 

 

 

 

“We will continue to monitor the situation and if we can return to the norm for example and without any surge in cases, then I think that is the balance that we want to achieve…but we need to step up in terms of surveillance in the hospital and among the community.

 

“We must  make sure that there is no sudden increase of cases although we have reopened the economic, social and education sectors,” he said at the daily press conference on COVID-19 today.

 

He said the MOH will continue to monitor the local transmission of the virus to make sure it is under control before moving to the next step which is to focus on the international border.

 

 

Dr Noor Hisham said apart from looking into the global index, Malaysia would consider discussing the agreed SOP between neighbouring countries like Singapore, Brunei and Thailand, before lifting the border restriction.

 

Meanwhile, Dr Noor Hisham said today saw the end of two more clusters namely the Selangor Mansion and the Sabah IPT clusters and with that, a total of  34 clusters have ended.

 

 

Source: BERNAMA News Agency

 

MOE optimistic of schools completing this year’s syllabus

The Ministry of Education (MOE) is optimistic that schools will have enough time to complete the syllabus for this year.

 

Education Minister, Dr Mohd Radzi Md Jidin said the government would restructure the school schedule this year when schools reopen on June 24.

 

“The MOE would like to assess the situation after schools reopen before finalising on the new school term,” he told reporters after a special media conference on the re-opening of schools in Perdana Putra here today.

 

 

 

According to Mohd Radzi, on June 24 all secondary and primary school teachers will return to school to conduct online learning and teaching using school facilities.

 

“By returning to school, teachers can use various facilities including the internet, photocopying and printing machines,” he said.

 

He added, teachers could provide weekly study and exercise materials in schools before asking their parents to collect them.

 

 

On the number of students in a classroom, he emphasised that what was important was that social distancing must be observed with tables set apart at a distance of one metre.

 

Commenting on the use of face masks among students at school, he said there was no objection to parents providing them for their children.

 

“As mentioned in the Ministry of Education’s guidelines, teachers will provide face masks when students are in school or have symptoms,” he said.

 

Meanwhile, Dr Mohd Radzi said the Ministry of Transport was finalising the standard operating procedures (SOPs) for school buses to ensure the safety and health of students.

 

 

 

Source: BERNAMA News Agency

Four Taiping prison ex-inmates grateful at job offers

 

TAIPING  Four former convicts of Taiping Prison get a new lease of life after they completed their jail terms and secure jobs through an employment placement programme by the Malaysian Prison Department.

 

They would be hired by a construction company, APG Steel Enterprise to work in a project to construct a building in Nilai, Negeri Sembilan.

 

One of them, known only as Azhar, 34, had decided to make use of the opportunity in the best possible manner to help him get on with his life.

 

 

 

The Bagan Serai native was released from the prison on May 24 after serving a six-month jail term for a drug-related offence and was determined to be a good worker.

 

“I am grateful to the department for helping me to get a job after leaving prison,” he said when met at the programme in the compound of the Taiping Prison here today.

 

Another ex-convict, Fuad, 32, who was released on June 1 after serving a six-month sentence, also for drug-related offence, was also grateful at the opportunity to start a new life.

 

 

“I will work hard for my family and myself. Thank you for accepting us, ex-convicts,” he said. He hailed from Trong near here.

 

Meanwhile, APG Steel Enterprise manager Mohd Muhlis Sukir said the programme is an excellent initiative by the department because it helped him to find local workers for the construction company.

 

In the meantime, Taiping Prison director Mohd Farid Kasim said 45 ex-convicts had been placed in various employment sectors in Pahang, Negeri Sembilan, Penang, Johor and Selangor since January.

 

The programme aims to provide an opportunity for former inmates to build a new life so that they would not be abandoned and marginalised by society.

 

“Besides, through the programme, we are heeding the call of the government to replace foreign workers with locals in the country’s construction sector,” he said.

 

 

Source: BERNAMA News Agency